Farming Orbs of Chance efficiently in Path of Exile 2 involves a combination of targeted strategies, understanding drop mechanics, and optimizing your gameplay environment to maximize returns.

The most basic method to acquire Orbs of Chance is by killing monsters. Higher-level monsters and rarer monster types such as magic, rare, and unique enemies have a better chance of dropping valuable currency, including Orbs of Chance. Therefore, focusing on areas with high monster density and higher-level enemies significantly increases your chances. Progressing through the Atlas of Worlds and farming in higher-tier maps is particularly effective, as these areas yield more currency drops overall.

Strongboxes and chests are also valuable sources. Opening strongboxes with modifiers that increase currency drops or item quantity can yield multiple Orbs of Chance. Always prioritize opening these containers during your runs, especially those with beneficial modifiers like "Currency" or "Diviner," which enhance the likelihood of valuable drops.

Magic Find, or increasing your item rarity stat, indirectly boosts your chance of obtaining Orbs of Chance by increasing the total number of items dropped. Equipping gear, flasks, or passive skills that raise item rarity can therefore improve your farming efficiency.

Certain bosses and rare enemies have higher drop rates for Orbs of Chance. While specific bosses are not officially confirmed to have guaranteed drops, targeting bosses with multiple phases or higher difficulty is a common strategy. Additionally, you can reset boss instances to farm them repeatedly, increasing your orb acquisition over time.

Another farming avenue involves collecting Chance Shards, which are fragments that combine into a full Orb of Chance when you gather ten. These shards drop more frequently than full orbs, especially from Cruel difficulty onward and in endgame content. You can also obtain Chance Shards by disenchanting unique items through specific vendors in hub towns, providing a reliable, though slower, method to accumulate Orbs of Chance. Players who prefer to avoid the grind sometimes look to buy poe 2 currency to speed up their progression.

To maximize the value of your farming, focus on acquiring base items that have a higher potential to turn into valuable magic, rare, or unique items when chanced. Items with multiple affix slots, such as helmets, gloves, boots, or rare flasks, are excellent targets. Prioritize bases that are in demand or commonly used in high-level crafting and builds, as these will yield better returns when successfully upgraded.

Utilizing league mechanics and events can further enhance farming. Some leagues introduce modifiers that increase item rarity or quantity, boosting your chances of finding Orbs of Chance and valuable base items. Staying updated on current league features and adapting your farming routes accordingly can improve efficiency. If you're working within a budget, sourcing cheap poe 2 currency from reliable vendors may offer a shortcut to your goals.

Patience and persistence are key. Farming Orbs of Chance is inherently random and may require many attempts before yielding significant results. Combining high-density monster farming, strongbox opening, boss farming, and strategic use of item rarity boosts will collectively improve your orb acquisition rate. By refining your approach and focusing on valuable base items, you can make the most of your Orbs of Chance farming efforts in Path of Exile 2.